Matthew Kutys, PhD
Assistant Professor
Cell and Tissue Biology
+1 415 502-2247
The Kutys Lab spans disciplinary boundaries between cell biology and engineering to answer fundamental questions in tissue morphogenesis and mechanobiology. We develop and apply biomimetic human tissue models, along with cellular and molecular technologies, to identify mechanisms across biological scales that govern cell-tissue structure and function. We aim to use these discoveries to inform the selection of candidate therapies and the design of next gen preclinical models for human cancer and cardiovascular disease. Current research thrusts include the role of Notch1 in multicellular mechanobiology and tumor suppression, chemo-mechanical signaling at adherens junctions during morphogenesis, and microfluidic human organoid platforms for developmental modeling.
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