Assistant Professor
Cell and Tissue Biology
The Gong lab studies how cell polarity controls the dynamic processes that drive tissue development, homeostasis, and regeneration. Our work uncovers fundamental principles of polarity that integrate signaling pathways with organelle organization. By harnessing this knowledge, we aim to engineer cells to guide development and combat disease. Currently, we are focusing on a novel form of structural polarity, which we term ER–PM contacts–dependent polarity. This polarity provides a fundamental mechanism for how cells decide when and where to move and may offer new insights into neurobiology, immunology, and developmental biology.
Publications
A Huluwa phosphorylation switch regulates embryonic axis induction.
Nature communications
Regulatory factor identification for nodal genes in zebrafish by causal inference.
Frontiers in cell and developmental biology
Maternal Factors and Nodal Autoregulation Orchestrate Nodal Gene Expression for Embryonic Mesendoderm Induction in the Zebrafish.
Frontiers in cell and developmental biology
Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14.
Nucleic acids research
A Golgi-derived vesicle potentiates PtdIns4P to PtdIns3P conversion for endosome fission.
Nature cell biology
Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis.
Nature communications
Alkbh4 and Atrn Act Maternally to Regulate Zebrafish Epiboly.
International journal of biological sciences
TGFß1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway.
Journal of molecular cell biology