Michael Mcmaster, PhD

Adjunct Professor
Cell and Tissue Biology
[email protected]
+1 415 514-0172
Michael McMaster is a developmental biologist and educator, and joined the UCSF faculty in 1994. Dr. McMaster is Director of the Biomedical Sciences stream with primary responsibility for the basic science curriculum in the first and second years of Dental School. He teaches gross anatomy, development, and neuroscience in the Dental, Medical and Graduate schools. Dr. McMaster has extensive expertise in medical education, particularly basic sciences as a foundation for clinical excellence. He is director of the School of Dentistry gross anatomy laboratory and has earned recognition for excellence in teaching. His research interests center on placental development, diseases of pregnancy and embryonic stem cell model systems for understanding the consequences of gestational exposures to environmental chemicals.
Publications: 

Organophosphate and organohalogen flame retardant exposure and thyroid hormone disruption in women firefighters and office workers from San Francisco.

ISEE Conference Abstracts

Jessica Trowbridge, Roy Gerona, Michael Mcmaster, Katerine Ona, Cassidy Clarity, Vincent Bessonneau, Ruthann Rudel, Heather Buren, Rachel Morello Frosch

Trisomy 21 is Associated with Caspase-2 Upregulation in Cytotrophoblasts at the Maternal-Fetal Interface.

Reproductive sciences (Thousand Oaks, Calif.)

Leon-Martinez D, Robinson JF, Zdravkovic T, Genbacev O, Gormley M, Mcmaster M, Fisher SJ, Bianco K

Placental Structure in Preterm Birth Among HIV-Positive Versus HIV-Negative Women in Kenya.

Journal of acquired immune deficiency syndromes (1999)

Obimbo MM, Zhou Y, McMaster MT, Cohen CR, Qureshi Z, Ong'ech J, Ogeng'o JA, Fisher SJ

Defective decidualization during and after severe preeclampsia reveals a possible maternal contribution to the etiology.

Proceedings of the National Academy of Sciences of the United States of America

Garrido-Gomez T, Dominguez F, Quiñonero A, Diaz-Gimeno P, Kapidzic M, Gormley M, Ona K, Padilla-Iserte P, McMaster M, Genbacev O, Perales A, Fisher SJ, Simón C

Cover Image, Volume 36, Issue 9.

Prenatal Diagnosis

Katherine Bianco, Matthew Gormley, Jason Farrell, Yan Zhou, Oliver Oliverio, Hannah Tilden, Michael McMaster, Susan J. Fisher

Placental transcriptomes in the common aneuploidies reveal critical regions on the trisomic chromosomes and genome-wide effects.

Prenatal Diagnosis

Bianco K, Gormley M, Farrell J, Zhou Y, Oliverio O, Tilden H, McMaster M, Fisher SJ

Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification.

Development (Cambridge, England)

Zdravkovic T, Nazor KL, Larocque N, Gormley M, Donne M, Hunkapillar N, Giritharan G, Bernstein HS, Wei G, Hebrok M, Zeng X, Genbacev O, Mattis A, McMaster MT, Krtolica A, Valbuena D, Simón C, Laurent LC, Loring JF, Fisher SJ

Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsia.

Journal of Clinical Investigation

Yan Zhou, Matthew J. Gormley, Nathan M. Hunkapiller, Mirhan Kapidzic, Yana Stolyarov, Victoria Feng, Masakazu Nishida, Penelope M. Drake, Katherine Bianco, Fei Wang, Michael T. McMaster, Susan J. Fisher

Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsia.

The Journal of clinical investigation

Zhou Y, Gormley MJ, Hunkapiller NM, Kapidzic M, Stolyarov Y, Feng V, Nishida M, Drake PM, Bianco K, Wang F, McMaster MT, Fisher SJ

Maternal decidual macrophages inhibit NK cell killing of invasive cytotrophoblasts during human pregnancy.

Biology of reproduction

Co EC, Gormley M, Kapidzic M, Rosen DB, Scott MA, Stolp HA, McMaster M, Lanier LL, Bárcena A, Fisher SJ

Human trophoblast progenitors: where do they reside?

Seminars in reproductive medicine

Genbacev O, Lamb JD, Prakobphol A, Donne M, McMaster MT, Fisher SJ

Establishment of human trophoblast progenitor cell lines from the chorion.

Stem cells (Dayton, Ohio)

Genbacev O, Donne M, Kapidzic M, Gormley M, Lamb J, Gilmore J, Larocque N, Goldfien G, Zdravkovic T, McMaster MT, Fisher SJ

Pre-eclampsia is associated with elevated CXCL12 levels in placental syncytiotrophoblasts and maternal blood.

European journal of obstetrics, gynecology, and reproductive biology

Schanz A, Winn VD, Fisher SJ, Blumenstein M, Heiss C, Hess AP, Kruessel JS, Mcmaster M, North RA

GROa regulates human embryonic stem cell self-renewal or adoption of a neuronal fate.

Differentiation; research in biological diversity

Krtolica A, Larocque N, Genbacev O, Ilic D, Coppe JP, Patil CK, Zdravkovic T, McMaster M, Campisi J, Fisher SJ

721: Global gene expression profiling of the maternal-fetal interface in common aneuploidies: identification of gene dosage-dependant phenotypes.

American Journal of Obstetrics and Gynecology

Katherine Bianco, Matthew Gormley, Gabriel Goldfien, Brittni Johnson, Michael McMaster, Mari-Paul Thiet, Susan Fisher

A proteomic approach identifies early pregnancy biomarkers for preeclampsia: novel linkages between a predisposition to preeclampsia and cardiovascular disease.

Proteomics

Blumenstein M, McMaster MT, Black MA, Wu S, Prakash R, Cooney J, McCowan LM, Cooper GJ, North RA

613: Chromosomal abnormalities and the risk for preeclampsia/eclampsia.

American Journal of Obstetrics and Gynecology

Katherine Bianco, Yvonne Cheng, Susan Fisher, Michael McMaster, Julie De La Garza, Aaron Caughey

Human embryonic stem cells as a model system for studying the effects of smoke exposure on the embryo.

Reproductive toxicology (Elmsford, N.Y.)

Zdravkovic T, Genbacev O, LaRocque N, McMaster M, Fisher S

Comparative analysis of maternal-fetal interface in preeclampsia and preterm labor.

Cell and tissue research

Zhou Y, Bianco K, Huang L, Nien JK, McMaster M, Romero R, Fisher SJ

Nicotine downregulates the l-selectin system that mediates cytotrophoblast emigration from cell columns and attachment to the uterine wall.

Reproductive toxicology (Elmsford, N.Y.)

Zdravkovic T, Genbacev O, Prakobphol A, Cvetkovic M, Schanz A, McMaster M, Fisher SJ

The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G.

Diabetes

Cirulli V, Zalatan J, McMaster M, Prinsen R, Salomon DR, Ricordi C, Torbett BE, Meda P, Crisa L

Expression of HLA-G in malignant mesothelioma and clinically aggressive breast carcinoma.

Virchows Archiv : an international journal of pathology

Kleinberg L, Flørenes VA, Skrede M, Dong HP, Nielsen S, McMaster MT, Nesland JM, Shih IeM, Davidson B

Serum-free derivation of human embryonic stem cell lines on human placental fibroblast feeders.

Fertility and sterility

Genbacev O, Krtolica A, Zdravkovic T, Brunette E, Powell S, Nath A, Caceres E, McMaster M, McDonagh S, Li Y, Mandalam R, Lebkowski J, Fisher SJ

The adverse effects of maternal smoking on the human placenta: a review.

Placenta

Zdravkovic T, Genbacev O, McMaster MT, Fisher SJ

HLA-G expression in effusions is a possible marker of tumor susceptibility to chemotherapy in ovarian carcinoma.

Gynecologic oncology

Davidson B, Elstrand MB, McMaster MT, Berner A, Kurman RJ, Risberg B, Trope CG, Shih IeM

HLA-G upregulation in pre-malignant and malignant lesions of the gastrointestinal tract.

International journal of gastrointestinal cancer

Hansel DE, Rahman A, Wilentz RE, Shih IeM, McMaster MT, Yeo CJ, Maitra A

Abnormal placentation and the syndrome of preeclampsia.

Seminars in nephrology

McMaster MT, Zhou Y, Fisher SJ

Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface.

The Journal of clinical investigation

Red-Horse K, Zhou Y, Genbacev O, Prakobphol A, Foulk R, McMaster M, Fisher SJ

Truncated HLA-G isoforms are retained in the endoplasmic reticulum and insufficiently provide HLA-E ligands.

Human immunology

Ulbrecht M, Maier S, Hofmeister V, Falk CS, Brooks AG, McMaster MT, Weiss EH

HLA-G is a potential tumor marker in malignant ascites.

Clinical cancer research : an official journal of the American Association for Cancer Research

Singer G, Rebmann V, Chen YC, Liu HT, Ali SZ, Reinsberg J, McMaster MT, Pfeiffer K, Chan DW, Wardelmann E, Grosse-Wilde H, Cheng CC, Kurman RJ, Shih IeM

Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies.

American Journal of Obstetrics and Gynecology

Taylor RN, Grimwood J, Taylor RS, McMaster MT, Fisher SJ, North RA

Placental Development.

Encyclopedia of Hormones

Michael T. McMaster, Susan J. Fisher

Histocompatibility leukocyte antigen-G is not expressed by endometriosis or endometrial tissue.

Fertility and sterility

Hornung D, Fujii E, Lim KH, Vigne JL, McMaster MT, Taylor RN

Concordant in situ and in vitro data show that maternal cigarette smoking negatively regulates placental cytotrophoblast passage through the cell cycle.

Reproductive toxicology (Elmsford, N.Y.)

Genbacev O, McMaster MT, Lazic J, Nedeljkovic S, Cvetkovic M, Joslin R, Fisher SJ

HLA-G, -E, -F preworkshop: tools and protocols for analysis of non-classical class I genes transcription and protein expression.

Human immunology

Paul P, Rouas-Freiss N, Moreau P, Cabestre FA, Menier C, Khalil-Daher I, Pangault C, Onno M, Fauchet R, Martinez-Laso J, Morales P, Villena AA, Giacomini P, Natali PG, Frumento G, Ferrara GB, McMaster M, Fisher S, Schust D, Ferrone S, Dausset J, Geraghty D, Carosella ED

HLA-G Does Not Mediate the Natural Killer Cell Suppression Associated with Endometriosis.

Fertility and sterility

D Hornung, E Fujii, K.-H Lim, J.-L Vigne, M.T McMaster, R.N Taylor

Posttranscriptional regulation of human leukocyte antigen G during human extravillous cytotrophoblast differentiation.

Biology of reproduction

Copeman J, Han RN, Caniggia I, McMaster M, Fisher SJ, Cross JC

Id-2 regulates critical aspects of human cytotrophoblast differentiation, invasion and migration.

Development (Cambridge, England)

Janatpour MJ, McMaster MT, Genbacev O, Zhou Y, Dong J, Cross JC, Israel MA, Fisher SJ

Upregulation of human cytotrophoblast invasion by hepatocyte growth factor.

Journal of reproduction and fertility. Supplement

Nasu K, Zhou Y, McMaster MT, Fisher SJ

Invasive cytotrophoblast apoptosis in pre-eclampsia.

Human reproduction (Oxford, England)

Genbacev O, DiFederico E, McMaster M, Fisher SJ

Oxygen Regulates Human Cytotrophoblast Proliferation, Differentiation, and Invasion: Implications for Endovascular Invasion in Normal Pregnancy and Preeclampsia.

Embryo Implantation

Olga Genbacev, Yan Zhou, Michael T. McMaster, John W. Ludlow, Caroline H. Damsky, Susan J. Fisher

HLA-G isoforms produced by placental cytotrophoblasts and found in amniotic fluid are due to unusual glycosylation.

Journal of immunology (Baltimore, Md. : 1950)

McMaster M, Zhou Y, Shorter S, Kapasi K, Geraghty D, Lim KH, Fisher S

Complementary expression of HIP, a cell-surface heparan sulfate binding protein, and perlecan at the human fetal-maternal interface.

Biology of reproduction

Rohde LH, Janatpore MJ, McMaster MT, Fisher S, Zhou Y, Lim KH, French M, Hoke D, Julian J, Carson DD

Human cytotrophoblast differentiation/invasion is abnormal in pre-eclampsia.

The American journal of pathology

Lim KH, Zhou Y, Janatpour M, McMaster M, Bass K, Chun SH, Fisher SJ

Identification of a thymic epithelial cell subset sharing expression of the class Ib HLA-G molecule with fetal trophoblasts.

The Journal of experimental medicine

Crisa L, McMaster MT, Ishii JK, Fisher SJ, Salomon DR

Tissue inhibitor of metalloproteinase-3 expression is upregulated during human cytotrophoblast invasion in vitro.

Developmental genetics

Bass KE, Li H, Hawkes SP, Howard E, Bullen E, Vu TK, McMaster M, Janatpour M, Fisher SJ

Human placental HLA-G expression is restricted to differentiated cytotrophoblasts.

Journal of immunology (Baltimore, Md. : 1950)

McMaster MT, Librach CL, Zhou Y, Lim KH, Janatpour MJ, DeMars R, Kovats S, Damsky C, Fisher SJ

Integrin switching regulates normal trophoblast invasion.

Development (Cambridge, England)

Damsky CH, Librach C, Lim KH, Fitzgerald ML, McMaster MT, Janatpour M, Zhou Y, Logan SK, Fisher SJ

Human trophoblast invasion. Autocrine control and paracrine modulation.

Annals of the New York Academy of Sciences

McMaster MT, Bass KE, Fisher SJ

Association of monocytes and neutrophils with early events of blastocyst implantation in mice.

Journal of reproduction and fertility

McMaster MT, Dey SK, Andrews GK

Activation and distribution of inflammatory cells in the mouse uterus during the preimplantation period.

Journal of immunology (Baltimore, Md. : 1950)

McMaster MT, Newton RC, Dey SK, Andrews GK

Lactoferrin in the mouse uterus: analyses of the preimplantation period and regulation by ovarian steroids.

Molecular endocrinology (Baltimore, Md.)

McMaster MT, Teng CT, Dey SK, Andrews GK

Endotoxin induction of murine metallothionein gene expression.

The Journal of biological chemistry

De SK, McMaster MT, Andrews GK

Cell type-specific expression of transforming growth factor-beta 1 in the mouse uterus during the periimplantation period.

Molecular endocrinology (Baltimore, Md.)

Tamada H, McMaster MT, Flanders KC, Andrews GK, Dey SK

Cell-specific metallothionein gene expression in mouse decidua and placentae.

Development (Cambridge, England)

De SK, McMaster MT, Dey SK, Andrews GK

Mouse and rat placental cell lines express abundant amounts of laminin.

Placenta

Soares MJ, McMaster MT, De SK, De M, Chang M, Jokhai S, Hunt JS